Terbium in PDB 8cr8: Human Interleukin-23

The structure of Human Interleukin-23, PDB code: 8cr8 was solved by Y.Bloch, S.N.Savvides, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	69.30 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	67.748, 59.842, 69.989, 90, 98.06, 90
R / Rfree (%)	23.5 / 25.6

The binding sites of Terbium atom in the Human Interleukin-23 (pdb code 8cr8). This binding sites where shown within 5.0 Angstroms radius around Terbium atom.
In total only one binding site of Terbium was determined in the Human Interleukin-23, PDB code: 8cr8:

Terbium binding site 1 out of 1 in the Human Interleukin-23


Mono view


Stereo pair view

A full contact list of Terbium with other atoms in the Tb binding site number 1 of Human Interleukin-23 within 5.0Å range: probe atom residue distance (Å) B Occ A:Tb401 b:72.0 occ:1.00 OE2 A:GLU22 2.4 63.9 1.0 OE1 A:GLU44 2.4 55.5 1.0 O A:HOH522 2.4 55.4 1.0 OE2 A:GLU44 2.4 56.1 1.0 OE1 A:GLU22 2.4 63.5 1.0 CD A:GLU44 2.7 55.9 1.0 CD A:GLU22 2.7 63.2 1.0 CG A:GLU44 4.2 56.3 1.0 CG A:GLU22 4.2 62.2 1.0 O A:GLY43 4.6 54.1 1.0 O A:HOH510 4.9 55.4 1.0 CB A:GLU22 4.9 62.4 1.0

Y.Bloch, J.Felix, R.Merceron, M.Provost, R.A.Symakani, R.De Backer, E.Lambert, A.R.Mehdipour, S.N.Savvides. Structures of Complete Extracellular Receptor Assemblies Mediated By Il-12 and Il-23. Nat.Struct.Mol.Biol. 2024.
ISSN: ESSN 1545-9985
PubMed: 38287195
DOI: 10.1038/S41594-023-01190-6